AOD-9604 vs tesamorelin: what is the difference?
AOD-9604 and tesamorelin are both associated with the growth-hormone axis, but they sit in completely different places in that story. One is a fragment of growth hormone itself, the other mimics the hormone that governs its release. Below they sit side by side.
| Property | AOD-9604 | Tesamorelin |
|---|---|---|
| Type | Fragment of human growth hormone (hGH 176-191) | GHRH analogue |
| Position in the GH axis | Fragment of the hormone itself | Mimics the releasing hormone |
| Research field | Metabolic research, adipose tissue | Growth-hormone axis, metabolic research |
| Peptide type | Peptide fragment (16 amino acids) | Stabilised GHRH analogue |
| Purity | ≥99% (HPLC + MS, Janoshik COA per batch) | ≥99% (HPLC + MS, Janoshik COA per batch) |
| Molecular weight | 1815.08 g/mol | See COA per batch |
| Vial strength | 5 mg per vial | 10 mg per vial |
Fragment versus analogue
AOD-9604 is a fragment of growth hormone itself (amino acids 176-191), while tesamorelin is an analogue of GHRH — the hormone that drives the release of growth hormone. That is a fundamental difference in focus: one is a piece of the message, the other mimics the sender.
Read the individual guides: what is AOD-9604 and what is tesamorelin.
Why are they compared?
Because both appear in metabolic research in the literature, they are often listed together. Even so they are not interchangeable: the choice follows entirely from the research design, and this is not dosing or usage advice.
See the range in fat loss & metabolism and muscle growth & growth hormone.
Frequently Asked Questions
What is the difference between AOD-9604 and tesamorelin?
AOD-9604 is a fragment of human growth hormone (amino acids 176-191). Tesamorelin is a GHRH analogue and therefore mimics the hormone that drives growth-hormone release. Different points of focus within the same axis.
Is AOD-9604 a growth-hormone secretagogue?
No. AOD-9604 is a fragment of growth hormone itself and not a secretagogue. GHRH analogues such as tesamorelin and GHRPs such as ipamorelin do fall under the secretagogues.
What does 176-191 refer to?
It refers to the position of the amino acids within human growth hormone: AOD-9604 is derived from the C-terminal fragment 176-191 of that molecule.
FOR RESEARCH USE ONLY. For laboratory and research purposes only. Not for human or animal consumption; not a medicine and does not constitute medical advice.